Who it may help
Mild to moderate knee osteoarthritis, patellar tendinopathy and some other tendon or ligament problems, when rehabilitation and simpler care have not been enough. Severe, bone-on-bone arthritis tends to respond less.
How it works
A small blood draw is spun in an FDA-cleared device to concentrate platelets. The PRP is injected into the knee joint or tendon under ultrasound guidance. Usually one to three injections are considered, followed by a progressive strengthening plan.
What the evidence shows
Meta-analyses of randomized trials suggest PRP improves pain and function in knee osteoarthritis for six to twelve months, compared with hyaluronic acid or steroid injections. One large trial found no difference from saline. We share both sides before you decide.
Risks
Temporary soreness and swelling for a few days are common. Infection is rare.
Common
questions.
Related conditions
Related treatments
From the Journal
Sources
- Belk JW, et al. Platelet-rich plasma versus hyaluronic acid for knee osteoarthritis: a systematic review and meta-analysis. Am J Sports Med. 2021.
- Bennell KL, et al. Effect of intra-articular platelet-rich plasma vs placebo injection on pain and medial tibial cartilage volume in patients with knee osteoarthritis. JAMA. 2021.
- American Academy of Orthopaedic Surgeons. Management of osteoarthritis of the knee (non-arthroplasty): evidence-based clinical practice guideline. 2021.
This page is general information, not medical advice. Individual results vary. Medical Disclaimer